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R&D Projects

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Call for Funding of Research and Development Projects in all Scientific Domains - 2009

Bioactivation routes of the anti-HIV drug Nevirapine: identification of reactive metabolites and mutagenic potential

PTDC/QUI-QUI/113910/2009

Main Research Area
Chemistry and Biochemistry - Chemistry
Keywords
Nevirapine
Metabolic activation
Mutagenicity/Carcinogenicity
Innovative 'in vitro' models
Funding
€ 133,000.00
Institutions
Main Contractor
Instituto Superior Técnico (IST/ULisboa)
Participating Institutions
Faculdade de Farmácia da Universidade de Lisboa (FF/ULisboa)
Faculdade de Ciências Médicas (FCM/UNL)
Main Research Unit
Centro de Química Estrutural (CQE/IST/ULisboa)
Team
Principal Investigator
Maria Matilde Soares Duarte Marques
Researchers
Michel Kranendonk
JOSE Alexandre Gusmão RUEFF Tavares
Alexandra Maria Moita Antunes
Pedro Paulo de Lacerda e Oliveira Santos
Joana Paiva Gomes Miranda
Maria da Conceição Monteiro André de Oliveira