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R&D Projects

Confirmed projects database queries

The information may be unavailable due to the results not being approved or confirmed. In particular, when a call includes regions where projects are cofunded by EC funds and others where that is not the case, confirmation or approval may be not simultaneous.

Call for Funding of Research and Development Projects in all Scientific Domains - 2008

Health Sciences - Pharmacology and Pharmacological Sciences

    Painel de Avaliação de Ciências da Saúde - 2008
  • Fernando Lopes da Silva
  • Roland Pochet
  • Alice Warley
  • David Chambers
  • Jean-Michel Bouler
  • George Griffin
  • Fernando Giraldez Orgaz
  • Francisco Bolumar
  • Ad Geurts van Kessel
  • Anton J. G. Horrevoets
  • Trevor W Stone
  • Richard K Grencis
  • Sergio Cerutti

Impact of methamphetamine on the blood-brain barrier: unmasking the underlying mechanisms and the role of neuroinflammation. Ana Paula Pereira da Silva Martins, Universidade de Coimbra (UC). €129,388.


Lung CYD-DDS (cyclodextrin-based drug delivery systems) for inhalation. Helena Maria Cabral Marques, Faculdade de Farmácia da Universidade de Lisboa (FF/ULisboa). €193,271.


Targeting the mitochondrial electron transport chain of malaria parasites: computer-assisted design and synthesis of bc1 complex inhibitors as antimalarial agents. Rui Moreira, Faculdade de Farmácia da Universidade de Lisboa (FF/ULisboa). €141,684.


Caloric restriction increases lifespan: role of neuropeptide Y on autophagy. Claudia Margarida Gonçalves Cavadas, Centro de Neurociências e Biologia Celular (CNBC/UC). €153,150.


EncapsDevice: Development of polymeric nanostructures for nasal and pulmonary delivery of peptides and proteins. Ana Margarida Moutinho Grenha, Universidade do Algarve (UAlg). €199,998.


Role of ATP and its P2Y1 receptors in neuroprotection. Rodrigo Antunes Cunha, Centro de Neurociências e Biologia Celular (CNBC/UC). €189,697.


Role of the neuregulin system in pulmonary arterial hypertension - pathophysiological and therapeutic implications. Carmen Dulce da Silveira Brás Silva, Faculdade de Medicina da Universidade do Porto (FM/UP). €86,952.


Implication of sirtuin proteins in the regulation of antigen presenting cells apoptosis during leishmaniasis: a therapeutic approach. Ricardo Jorge Leal Silvestre, Instituto de Biologia Molecular e Celular (IBMC/UP). €154,667.


Pharmacologic use of Gasotransmitters in Severe Malaria. Miguel Amado Franco Parreira Soares, Fundação Calouste Gulbenkian (FCG). €199,008.


Molecular and nanotechnology-based approaches to improve the antitumor activity of small molecules. Madalena Maria Magalhães Pinto, Faculdade de Farmácia da Universidade do Porto (FF/UP). €199,790.


Role and mechanism of action of immunoregulatory iNKT and DC cells in Leishmania infection: new approaches for vaccination? Anabela Cordeiro-da-Silva, Instituto de Biologia Molecular e Celular (IBMC/UP). €117,311.


A role for Nrf2/ARE cytoprotective signalling in iron overload. Adaptive response to oxidative stress as a disease modifier in HFE-associated hereditary hemochromatosis. Tiago Pereira de Lacerda Costa Duarte, Instituto de Biologia Molecular e Celular (IBMC/UP). €176,488.


A new life for old antimycobacterial drugs: development of prodrugs of pyrazinoic acid activated by mycobacterial esterases as a way to circumvent resistance to pyrazinamide. Luis Filipe Vicente Constantino, Faculdade de Farmácia da Universidade de Lisboa (FF/ULisboa). €192,882.


The Neuropeptide Y (NPY) and Dipeptidyl-peptidase IV (DPPIV) as new promising targets on the adipose tissue regulation in obesity. Joana Salgado, Centro de Neurociências e Biologia Celular (CNBC/UC). €96,184.


Enhancing the killing of intracellular multi-drug resistant tuberculosis (MDRTB) by human macrophages: a new chemotherapeutic strategy to fight MDRTB. MIGUEL VIVEIROS BETTENCOURT, Instituto de Higiene e Medicina Tropical (IHMT/UNL). €191,134.


IMPLICATIONS OF AMPHETAMINE PSYCHOSTIMULANTS ABUSE IN BRAIN AGING. João Paulo Capela, Instituto de Ciências e Tecnologias Agrárias e Agro-Alimentares - Porto (ICETA-Porto/ICETA). €199,488.


Monocarboxylate transporters as potential therapeutic targets in cancer: inhibition studies in solid tumor models. Maria de Fátima Monginho Baltazar, Universidade do Minho (UM). €119,711.


Development and validation of a pharmacokinetic/pharmacodynamic model to individualize carboplatin and gemcitabine doses for elderly patients with advanced non-small cell lung cancer. Paula Maria Façanha da Cruz Fresco, Instituto de Ciências e Tecnologias Agrárias e Agro-Alimentares - Porto (ICETA-Porto/ICETA). €138,154.


NanoFreeze - Freeze-drying approaches for overcoming instability of therapeutic proteins encapsulated into nanoparticles. Bruno Sarmento, Faculdade de Farmácia da Universidade do Porto (FF/UP). €197,150.


Anti-inflammatory mechanism and properties of medicinal plants: a multidisciplinary research for their validation and utilization as a source of phytopharmaceuticals. Maria Teresa Pereira Marques Batista, Universidade de Coimbra (UC). €177,553.


Analysis of transcription deregulation in brain and peripheral Huntington's disease models - influence of modulating histone deacetylases. Ana Cristina Carvalho Rego, Centro de Neurociências e Biologia Celular (CNBC/UC). €199,999.


Fibroblasts as mechano-sensory signalling intermediates between epithelia and primary afferent neurons: Role of extracellular ATP, purinoceptors and [Ca2+]i waves. Paulo Correia de Sá, Instituto de Ciências Biomédicas Abel Salazar da universidade do Porto (ICBAS/UP). €121,764.


Is there a place for adenosine mediating impairment of both neuromuscular and immunological synapses in myasthenics? Laura Oliveira, Instituto de Ciências Biomédicas Abel Salazar da universidade do Porto (ICBAS/UP). €103,995.