PerMed European Partnership Call 2025

The European Partnership EP PerMed, cofunded by the European Union (EU) under Horizon Europe, is a platform for joint programming of national and European research and innovation supporting activities putting into action “The Strategic Research & Innovation Agenda (SRIA) for Personalised Medicine (2023)”, SRIA for PM (2023), through dedicated research, development and innovation funding.

Topics

The EP PerMed joint transnational call 2025 (JTC2025), co-funded by the EU, aims to fund multinational research projects on pharmacogenomic strategies for Personalised Medicine  approaches that address one or more of the following aspects:

• Identification of new pharmacogenomic markers or signatures using (multi)-omics data in relation to drug or drug combination.
• Validation of a pharmacogenomic marker or signatures using (multi)-omics data in predicting drug or drug combination outcomes.
• Use pharmaco-omics strategies to determine the right dosage, the efficacy of treatments and/or the risk of adverse drug response and non-response to treatment to tailor personalised treatment pathways, including combined treatments (multi-medication).

Projects are encouraged to combine the following aspects in their research: 1) -omics data, 2) information regarding patient medication (prescription and non-prescription), dose or compliance; 3) information regarding clinical and environmental factors that are known to impact medication efficacy and adverse effects; and 4) information regarding medication efficacy, adverse effects and patient reported outcomes (PRO).

The following are individual or co-promotion beneficiaries:

a) Non-entrepreneurial entities of the R&I system, namely:

    i. Higher education institutions, their institutes and R&D units;

    ii. State, Associated or International Laboratories based in Portugal;

   iii. Private non-profit institutions whose main purpose is R&D activities, including Collaborative Laboratories (CoLab) and Technology and Innovation Centres (TIC);

   iv. Other non-profit public and private institutions developing or participating in scientific research activities.

b) Companies of any nature and in any legal form.

The information contained in this section does not exempt you from consulting Article 3 of the Regulation of projects financed exclusively by national funds, Regulation no. 5/2024, of 3 January, which amends and republishes Regulation no. 999/2016, of 31 October (see FCT Regulation, available in the 'Call Documents' area).

The EP PerMed JTC2025 consists of the submission of pre-proposals (1st phase) and full proposals (2nd phase). Only the pre-proposals submitted by the transnational consortia in the 1st phase may be invited to submit full proposals in the 2nd phase.

Each Proposing Institution (PI) that is part of a transnational consortium can only apply for funding from the PFA of its country or region. See the Guidelines for Aplicants and the Call Text (under Call Documents), for information on the eligibility rules of each PFA and on the transnational eligibility rules. For a proposal to be eligible, it must comply with the national and transnational eligibility rules.

To submit their application, each Portuguese PI wishing to apply for funding from FCT should:

1. Consult the Call Documents area.

2. Consult FCT eligibility rules (see Guideline for Applicants).

3. Submit, by the transnational consortium coordinator, the proposal form on the application submission platform (see Important links) until 13:00 GMT in mainland Portugal on 18/2/2024].

4. Send to FCT, within 10 working days after the deadline for submitting the application, a Statement of Commitment (SoC) completed and signed by the Portuguese Researcher in Charge (RC) identified by the PI and by a qualified representative of the PI. The SoC should be sent to the email address indicated in Contacts.

Please note:

• Failure to send the SoC to FCT on the date referred to in paragraph 4, or the unjustified delivery of the SoC after that deadline, or the delivery of an incomplete SoC, without one of the two parts – RC and PI – that make it up or without the signatures of the Portuguese RC and/or a qualified representative of the Portuguese PI, will result in the application being declared ineligible.
• If two or more Portuguese applicants from the same transnational consortium apply for funding from FCT, each must send a completed and signed SoC to FCT.
• One SoC must be sent to FCT for each application submitted by the same RC and PI.
• Portuguese partners of transnational consortia that do not apply for funding from FCT do not need to submit the SoC to FCT.
• The PI stamp or white seal is only required on manually signed SoC.

The information on this page is only a summary of the call, does not exempt the candidates from carefully reading all the call documents available on this page and on the call website (see Important links) and refers only to FCT’s participation in this call, unless expressly indicated.

Eligibility

The eligibility check of applications is carried out at both stages of the call (pre-proposal submission stage and full proposal submission stage):

• National/Regional Funding Agencies check national eligibility of applications, ensuring compliance with the formal requirements in the applicable national/regional regulations and other applicable documents (see FCT Regulation, Normas de execução financeira and national annexes in the Call Documents area).
• Transnational eligibility check of applications will be performed by the Call Secretariat, according to the transnational eligibility criteria presented in the Call Text in the Call Documents area.

Please note:

• For a proposal to be declared eligible it must fulfil both the national and transnational criteria.
• FCT, CCDRC and VP-GRA, as Portuguese funding agencies on this call, reserve the right to evaluate the possibility of transferring application(s) to other Portuguese funding agency/agencies if an application is considered non-eligible by the funding agency selected by the candidate institution, but is eligible by the other Portuguese funding agency/agencies. The transfer of applications will be carried out in accordance with the terms set out in the MoU signed between the parties.

Evaluation

The call includes two evaluation phases:

• Pre-proposal evaluation stage.
• Full proposal evaluation stage.

Proposals will be evaluated according to the evaluation criteria described in the Call Text in the Call Documents area.

The participating national/regional funding agencies, will decide, according to the stage the call is at, which 1) pre-proposals to invite to submit a full proposal and which 2) proposals to recommend for funding.

• FCT financial commitment for the call: 300 000,00 €
• Maximum requested funding for a consortium with Portuguese coordination: 150 000,00 €
• Maximum requested funding for a consortium with Portuguese participation: 100 000,00 €

Please note:

• Portuguese institutions funding must follow FCT’s Regulation on projects funded solely by national funds, Regulation no. 5/2024, of 3 January, which amends and republishes Regulation no. 999/2016, of 31 October (see FCT Regulation and Normas de execução financeira, both available in the Call Documents area, and the applicable national and European legislation).
• If more than one Portuguese applicant from the same transnational consortium applies for funding from FCT, the combined budget requested from FCT by the Portuguese applicants may not exceed the maximum funding limit for a consortium with Portuguese coordination (150 000,00 €) or with Portuguese participation (100 000,00 €). The Portuguese applicants of the same transnational consortium will have to share the funding that will be granted by FCT.
• The dedication (FTE) in transnational projects is not considered for the 100% (FTE) dedication to national projects.
• Under the terms of number 2 of Article 7 of the Regulation on projects funded solely by national funds, payments made directly or indirectly to companies through the Proposing Institution cannot exceed 50% of the total cost of the company’s participation.
• Each Portuguese applicant from the same transnational consortium may only apply for funding from one Portuguese participating funding agency, FCT, CCDRC or VP-GRA.
• If two or three Portuguese Proposing Institutions (PI) from the same international consortium apply for funding from the Portuguese agencies FCT and CCDRC, the total budget to be requested to these two agencies cannot exceed the cumulative sum per consortium of 100 000,00 € (Portuguese participation) or 150 000,00 € (Portuguese coordination) per consortium. This rule does not apply to institutions from Região Autónoma dos Açores applying for funding to VP-GRA and participating in a consortium with institutions applying for funding to FCT and/or CCDRC.
• If FCT, CCDRC or VP-GRA reach the limit of the budget that each of the agencies has set for funding projects under this call before the number of projects selected for funding by each of these agencies is exhausted, the projects selected for funding that do not have funding may be transferred to the agency that still has the budget to fund projects, provided that the respective eligibility criteria are met. The transfer of projects recommended for funding will be carried out in accordance with the conditions set out in the Memorandum of Understanding signed between the parties.

Call website

Matchmaking platform

Application submission platform

Partnership website

Partnership page on FCT’s website

Rita Cavaleiro e Pedro Ferreira

EPPerMed@fct.pt