EP PerMed European Partnership Call 2027

The European Partnership EP PerMed, cofunded by the European Union (EU) under Horizon Europe, is a platform for joint programming of national and European research and innovation supporting activities putting into action “The Strategic Research & Innovation Agenda (SRIA) for Personalised Medicine (2023)”, through dedicated research, development and innovation funding.

The EP PerMed 2027 joint transnational call aims to fund research projects in human health on Cell and Gene Therapy (CGT) for Personalised Medicine (PM) approaches. Proposals must focus on the development and validation of an innovative and novel CGT for PM.

The general theme of the Call is « Cell and Gene Therapy for Personalised Medicine». At least one of the following approaches must be employed:

• Somatic cell therapeutics (e.g., in the form of stem cells, organoids, or cells of the immune system);
• Gene therapeutics in the form of gene substitution, addition or suppression therapies using viral and non-viral vectors or genome editing;
• Combined cell- and gene therapeutics in the form of genetically modified cells;
• Novel biological products such as mRNA, other nucleic acid-based methods, and extracellular vesicles as vehicle for gene-based therapeutic procedure.

The following are individual or co-promotion beneficiaries:

a) Non-entrepreneurial entities of the R&I system, namely:

    i. Higher education institutions, their institutes and R&D units;

    ii. State, Associated or International Laboratories with head office in Portugal;

   iii. Non-profit private institutions whose main object is R&D activity, including Collaborative Laboratories (CoLab) and Technology and Innovation Centres (CTI).

   iv. Other non-profit public and private institutions developing or participating in scientific research activities.

b) Companies of any type and under any legal form.

The information contained in this section does not exempt you from consulting Article 3 of FCT’s Regulation No. 999/2016, in its current wording, i.e., as amended and republished by Regulation No. 5/2024 and corrected by Rectification Statement No. 366/2024/2, of 23 May 2024 (see FCT Regulation in Call Documents and the applicable national and European Union legislation).

The EP PerMed 2027 call consists of the submission of pre-proposals (1st phase) and full proposals (2nd phase). Only the pre-proposals submitted by the transnational consortia in the 1st phase may be invited to submit full proposals in the 2nd phase.

Each Proposing Institution (PI) that is part of a transnational consortium can only apply for funding from the Participating Funding Agencies (PFA) of its country or region. See the Call Text and Guidelines for Applicants (under Call Documents), for information on the eligibility rules of each PFA and on the transnational eligibility rules. For a proposal to be eligible, it must comply with the national and transnational eligibility rules.

To submit their application, each Portuguese PI wishing to apply for funding from FCT should:

1. Consult the Call Documents area.
2. Consult FCT eligibility rules (see Guideline for Applicants).
3. Submit, by the transnational consortium coordinator, the proposal form on the application submission platform (see Important links) until 13:00 GMT in mainland Portugal on 20/01/2027.
4. Send to FCT, within 10 working days after the deadline for submitting the application, a Statement of Commitment (SoC) completed and signed by the Portuguese Researcher in Charge (RC) identified by the PI and by a qualified representative of the PI. The SoC should be sent to the email address indicated in Contacts.

Please note:

• Failure to send the SoC to FCT on the date referred to in paragraph 4, or the unjustified delivery of the SoC after that deadline, or the delivery of an incomplete SoC, without one of the two parts – RC and PI – that make it up or without the signatures of the Portuguese RC and/or a qualified representative of the Portuguese PI, will result in the application being declared ineligible.
• If two or more Portuguese applicants from the same transnational consortium apply for funding from FCT, each must send a completed and signed SoC to FCT.
• One SoC must be sent to FCT for each application submitted by the same RC and PI.
• Portuguese partners of transnational consortia that do not apply for funding from FCT do not need to submit the SoC to FCT.
• The PI stamp or white seal is only required on manually signed SoC.

The information on this page is only a summary of the call, does not exempt the candidates from carefully reading all the call documents available on this page and on the call website (see Important links) and refers only to FCT’s participation in this call, unless expressly indicated.

Eligibility

The eligibility check of applications is carried out at both stages of the call (pre-proposal submission stage and full proposal submission stage):

• National/Regional Funding Agencies check national eligibility of applications, ensuring compliance with the formal requirements in the applicable national/regional regulations and other applicable documents (see FCT Regulation, Normas de execução financeira and national annexes in the Call Documents area).
• Transnational eligibility check of applications will be performed by the Call Secretariat, according to the transnational eligibility criteria presented in the Call Text in the Call Documents area.

Please note:

• For a proposal to be declared eligible it must fulfil both the national and transnational criteria.

Evaluation

The call includes two evaluation phases:

• Pre-proposal evaluation stage.
• Full proposal evaluation stage.

Proposals will be evaluated according to the evaluation criteria described in the Call Text in the Call Documents area.

The participating national/regional funding agencies, will decide, according to the stage the call is at, which 1) pre-proposals to invite to submit a full proposal and which 2) proposals to recommend for funding.

•    FCT financial commitment for the call: 300.000,00€
•    Maximum requested funding for a consortium with Portuguese coordination: 150.000,00€
•    Maximum requested funding for a consortium with Portuguese participation: 100.000,00€

Please note:

• Portuguese institutions funding must follow FCT’s Regulation No. 999/2016, in its current wording, i.e., as amended and republished by Regulation No. 5/2024 and corrected by Rectification Statement No. 366/2024/2, of 23 May 2024 (see FCT Regulation and Normas de execução financeira in Call Documents and the applicable national and European legislation).
• If two Portuguese applicants from the same transnational consortium apply for funding from FCT, the combined budget requested from FCT by the Portuguese applicants may not exceed the maximum funding limit for a consortium with Portuguese coordination (250.000,00€) or with Portuguese participation (150.000,00€). The Portuguese applicants of the same transnational consortium will have to share the funding that will be granted by FCT.
• The dedication (FTE) in transnational projects is not considered for the 100% (FTE) dedication to national projects.
• Under the terms of number 2 of Article 7 of the Regulation on projects funded solely by national funds, payments made directly or indirectly to companies through the Proposing Institution cannot exceed 50% of the total cost of the company’s participation.
• Within the scope of this call, the indirect costs are a fixed rate of 25% of all the estimated eligible direct costs. The expenses for the adaptation of buildings and facilities are limited to a maximum of 10% of the project’s total eligible expenses.
• Each Portuguese applicant from the same transnational consortium may only apply for funding from one Portuguese participating funding agency, FCT or VP-GRA.

• Call website
• Matchmaking platform
• Application submission platform
• Partnership website
• Partnership page on the FCT website
• CiênciaVitae Guide

Rita Cavaleiro

Pedro Ferreira

eppermed@fct.pt